The white spotting pattern is due to the insertion of feline endogenous retrovirus in the KIT gene. This gene disrupts the migration of melanocytes to certain areas of skin, resulting in areas of white. Female: Oo (orange and black or brown, referred to as tortoiseshell)įor the orange and white coat combination, the cat must also inherit the codominant white spotting gene (W S). ![]() The reason for the patchwork effect in female cats heterozygous for the O gene (Oo) is X chromosome inactivation – one of the X chromosomes in every cell in the embryo is randomly inactivated, and the gene on the other X chromosome is expressed.īelow shows what colour the offspring will be with different combinations. As the female has two X chromosomes, if she inherits the O gene from one parent and the o (non-orange) gene from the other parent, she will be a mixture of orange and non-orange (usually black or brown). The O gene is located on the X chromosome, the female has two X chromosomes (XX), while the male has one X and one Y (XY). The orange (O) gene is dominant, which means if the cat inherits one copy of the O gene from a parent, it will override any other colours, however, this is where it becomes a bit confusing. It consists of a red tabby colour intermingled with white. A ginger and white cat is a type of coat colour and pattern commonly found in mixed breed as well as purebred cats.
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